Gerhard F. Weinbauer,Friedhelm Vogel's Challenges in Nonhuman Primate Research in the 21st Century PDF

By Gerhard F. Weinbauer,Friedhelm Vogel

ISBN-10: 3830928394

ISBN-13: 9783830928393

In continuation of the Covance Primate Symposium sequence, the nineteenth Covance Primate Symposium came about in Münster on twenty third & twenty fourth of may perhaps 2012. Altogether, 70 individuals representing forty three companies, accrued for this symposium.
The 2012 Primate Symposium focussed on ?Challenges in Nonhuman Primate study within the twenty first Century?. The large participation and the full of life discussions through the symposium underlined the timeliness and significance of this subject. specialist audio system coated 4 significant themes, i.e. biosimilars improvement: regulatory implications, key issues and subsequent steps, optimizing nonhuman primate use in nonclinical defense evaluation, tendencies in nonhuman primate developmental & reproductive toxicology (DART) and juvenile toxicity review, and relevance and significance of nonhuman primate versions in regulatory toxicology. the improvement of biosimilar has taken up velocity significantly and in the meantime should be thought of a major factor of strength drug improvement, but there are nonetheless a few uncertainties und guidance are less than improvement. With the elevated specialise in biopharmaceuticals and the linked elevate for utilizing nonhuman primates being the appropriate animal version, it grew to become essential to optimize using this animal version, e.g. refine learn designs and animals numbers yet nonetheless execute significant preclinical stories. it seems that major development has been accomplished in that context. within the zone of nonhuman primate DART and juvenile toxicity overview, contemporary instruction alterations had an important impression on species choice, and the experimental layout plus the timing of those experiences in the preclinical programmes. ultimately, given the expanding laws and justficiations of utilizing nonhuman primates as experimental versions. it truly is paramount to appreciate the basic and imperative position that nonhuman primates can play in drug safeguard review and scientific drug development.

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Challenges in Nonhuman Primate Research in the 21st Century by Gerhard F. Weinbauer,Friedhelm Vogel


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